Clinical Research Nurse II - Oncology (San Diego)

Job Title: Clinical Research Nurse II (Oncology) Location: Onsite – San Diego, CA Schedule: Full-Time, Monday - Friday (flexible hours; no overtime expected) Compensation: $150,000 – $250,000 annually Position Overview: An oncology research site is seeking an experienced Clinical Research Nurse II to support and help lead oncology clinical trials. This role will function as both a research nurse and team lead, acting as a key clinical and operational partner across research trials. The Clinical Research Nurse II will serve as a central point of coordination between physicians, clinical research staff, and patients, while also helping bring structure, accountability, and strong clinical judgment to a growing program.

This is an excellent opportunity for a research nurse who thrives in a collaborative environment and is ready to take on increased ownership and informal leadership responsibilities. Key Responsibilities: Serve as the primary clinical resource for oncology clinical trials Act as a lead nurse and day-to-day resource for research staff, helping guide workflow, answer questions, and support trial execution Collaborate closely with a team of physicians, including two primary physician partners, as well as Clinical Research Coordinators (CRCs) Coordinate and manage patient care within clinical trials, including screening, enrollment, treatment administration support, and follow-up Ensure adherence to study protocols, regulatory requirements, and institutional standards, helping reinforce compliance and best practices Partner with investigators and study teams to resolve clinical and operational challenges in real time Support communication with sponsors, monitors, and internal stakeholders as needed Contribute to process improvements and help establish more structured, compliant workflows across the team Function in a Research Nurse Case Manager capacity, maintaining continuity of care for study participants Qualifications: Active Registered Nurse (RN) license in California Bachelor of Science in Nursing (BSN) required Minimum of 2+ year of clinical research nursing experience Oncology nursing experience required; pancreatic cancer experience strongly preferred ONS (Oncology Nursing Society) certification required or willingness to obtain within a defined timeframe Experience supporting clinical trials, including patient management and protocol adherence Comfortable working closely with physicians in a collaborative, fast-paced environment Academic medical center experience is a plus, but not required Key Competencies: Strong clinical judgment and decision-making skills, with the confidence to operate independently and advocate for best practices Ability to navigate complex situations and maintain accountability across teams Excellent interpersonal and communication skills, particularly in working with physicians and cross-functional teams Detail-oriented with a strong commitment to patient safety, protocol compliance, and data integrity Adaptable and solutions-oriented, with the ability to bring structure to evolving processes Team-oriented mindset with the ability to influence without direct authority