Medical Director, Clinical Development, Respiratory

Medical Director, Clinical Development, Respiratory Location: UK – London – New Oxford Street, USA - Massachusetts - Boston, USA - Pennsylvania - Upper Providence Posted Date: Apr 1 2026 Key Responsibilities Contribute to project team discussions on indication planning and incorporate input from across disciplines (scientific, clinical, commercial, regulatory, stats, etc) to support vital deliverables including the Target Medicine Profile (TMP), clinical development plan (CDP), study protocols, and integrated evidence strategy (IES) and planning. Provide effective support to the development and execution of the IES, including oversight of R&D evidence generation activities to ensure patient safety and study delivery. Design and execute clinical development plans across advanced stages of development, reflecting internal and external stakeholder input.

Contribute to ambitious clinical development timelines by overseeing development of clinical study protocols, amendments, investigator brochures, clinical study reports etc. Input to, and may lead, regulatory interactions and documents including briefing documents, presentations, addressing questions and responses for assigned studies and programs. Provide medical monitoring and oversight of the safety of study participants.

Act as clinical lead for a clinical study, taking a key role on the Study Leadership Team (SLT) and serve as clinical point of contact for a clinical study on the Clinical Matrix Team (CMT), across the internal matrix and a broad range of external experts. Make significant contributions to global regulatory submissions/files (e.g., IND, NDA, BLA, MAA), including briefing documents, presentations, and responses to regulatory questions. Evaluate specific business development activities, including due diligence and contribute to the implementation and embedding of strategic/organizational initiatives in Clinical Development, adopting innovative methodologies and processes including digital tools and technology.

Stay abreast of advancements in therapeutic area research, clinical trial methodologies, competitive environment, and regulatory space to maintain GSK’s competitive edge. Additional Expectations Demonstrate flexibility and adaptability in changing environments and ability to analyze incomplete information, identify potential risks and implications, and make informed decisions. Demonstrate enterprise mindset with effective collaboration across the matrix, able to integrate cross-functional knowledge into decision-making processes and balance team objectives with the wider business goals.

Embrace challenge as an opportunity, proactively generating ideas for innovative improvement and promoting an environment for others to be creative. Manage conflicts effectively and independently, negotiating mutually acceptable solutions. Analyze, interpret and critically evaluate data, information and digital content to interpret complex information, anticipate obstacles and identify potential solutions.

Consistently achieve desired outcomes through strong influencing skills including understanding others' perspectives, building trust, tailoring communications depending on the audience and using persuasive arguments to gain support. Basic Qualifications Medical Degree. Completion of formal postgraduate clinical training (e.g., Internal Medicine, Primary Care / Family Medicine), leading to board eligibility or certification.

Experience in clinical research and drug development, including experience relevant to respiratory diseases. Preferred Qualifications Medical degree with formal specialty training and board qualification/registration in Pulmonary Medicine, Pulmonary & Critical Care, or Respiratory Medicine. Experience working in the global pharmaceutical or biotechnology industry within respiratory diseases.

Experience leading global clinical trials and contributing to NDA, BLA, or MAA submissions. Experience in late‑stage respiratory drug development, including design, initiation, execution, and closure of Phase 2 and Phase 3 clinical trials. If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $222,750 to $371,250.

If you are based in another US location, the annual base salary range is $202,500 to $337,500. Compensation & Benefits The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. The position offers an annual bonus and eligibility to participate in GSK’s share based long‑term incentive program.

Benefits include health care and other insurance benefits for employee and family, retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. Equal Opportunity Employment GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. #J-18808-Ljbffr