Director, Clinical Development

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS‑addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity The Director, Clinical Development will contribute to the scientific, clinical, and operational scope of assigned study protocols. This role will work with cross‑functional teams for the design, execution, and monitoring of clinical studies, as well as oversee data review, interpretation, and communication to both internal and external stakeholders. Oncology and/or late‑stage experience is preferred.

Develop and execute clinical development strategies and the Clinical Development Plan (CDP) with a focus on early‑phase development. Lead cross‑functional teams with oversight from senior team members to conduct clinical studies, including study start‑up, execution and close‑out activities, data review/analysis, and preparation of study reports. Oversee the development of program‑level documents, including but not limited to clinical protocols, investigator’s brochure, clinical study reports, abstracts and manuscripts, presentations, and various other internal and external documents and communications as needed.

Conduct ongoing data reviews; prepare and present summaries to internal and external stakeholders. Ensure trial implementation according to the protocol and analyze information to assess issues relating to protocol conduct and/or individual subject safety. Interact with internal and external stakeholders (investigators, study sites, vendors, committees, etc.) in support of clinical trial objectives; respond to or triage questions for appropriate escalation.

Conduct literature reviews as needed. Travel: Up to 20%. Required Skills, Experience and Education A PhD, PharmD or equivalent is required.

The years of experience are based on clinical development or similar relevant experience. Minimum 8+ years of experience in the pharmaceutical or biotechnology industry as a clinical scientist or related role. Proven leadership in a collaborative team setting and driven by a desire to deploy innovative approaches and technologies in a high‑energy environment.

Detail‑oriented with ability to prioritize tasks and function independently as appropriate. Strong organizational skills and an ability to interpret, discuss, and report trial/program level data effectively and identify trends. Proficient with software tools (Microsoft Office), Electronic Data Capture, and other custom web‑based software.

Excellent written and verbal communication skills. Preferred Skills Strong experience with clinical data review and data quality assurance. Knowledge and experience with clinical trial management and oversight.

Understanding and experience in clinical trial protocol and regulatory document authoring. Base Pay Salary Range For candidates working onsite at our headquarters in Redwood City, CA, the base pay salary range is $211,000 – $264,000 USD. Revolution Medicines is an equal‑opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. #J-18808-Ljbffr