Weekend Engineering Area Manager

Job ID R0179598 – Date posted 05/07/2026 – Location Los Angeles, California About the role The Weekend Engineering Area Manager leads all Engineering and Maintenance support activities at the Takeda Los Angeles site during weekends and holidays. This role serves as the single point of contact for Manufacturing during assigned coverage, ensuring the safe, compliant, and reliable operation of manufacturing, utility, and facility systems in a 24/7 GMP environment. This position provides direct leadership to weekend swing and night maintenance supervisors and technicians, with strong dotted‑line oversight of Automation, Critical Systems, Refrigeration, Facilities/ISS, and other on‑call engineering resources.

Acting under delegated authority from site engineering leadership, the role is responsible for real‑time issue resolution, escalation, and coordination in alignment with Takeda’s PTRB principles. This role is critical to maintaining uninterrupted operations, protecting patient supply, and upholding Takeda’s standards for safety, quality, compliance, and reliability outside of standard business hours. Responsibilities Serve as the primary Engineering and Maintenance leader on‑site during weekends and holidays Act as the single point of contact for Manufacturing on all engineering, maintenance, utilities, automation, and facility‑related issues Lead and develop weekend maintenance supervisors and technicians, ensuring clear priorities and accountability Coordinate and direct cross‑functional engineering resources through strong dotted‑line leadership Lead real‑time troubleshooting across equipment, automation systems, utilities, and infrastructure to minimize downtime Assess safety, quality, compliance, and operational risk; make timely, GMP‑aligned decisions Escalate issues appropriately and engage SMEs or site leadership as needed Ensure systems are restored to a safe, stable, and fully operational condition before handoff to weekday teams Enforce compliance with FDA, cGMP, EHS, GEP, and site procedures Serve as the escalation point for safety incidents, environmental events, and GMP concerns Drive urgency, accountability, and disciplined execution across weekend operations Ensure effective shift handovers, documentation, and communication of risks and follow‑ups Coordination & Communication Partner closely with Manufacturing, Quality, EHS, and Supply Chain to minimize operational impact Provide concise updates to site leadership on critical events, risks, and recovery actions Ensure thorough documentation of issues, actions taken, and outstanding items for follow‑up Qualifications Bachelor’s degree in Engineering (Mechanical, Chemical, Electrical preferred); advanced degree (MBA/Master’s) a plus 6+ years of experience in engineering, maintenance, or technical operations 1+ year of leadership experience in a supervisory capacity Proven leadership experience managing supervisors and technical teams in a manufacturing environment Ability to lead cross‑functional engineering teams through direct and dotted‑line authority Strong troubleshooting and decision‑making skills in time‑critical situations Working knowledge of maintenance, automation, utilities, and facility systems Solid understanding of cGMP, EHS, and regulatory requirements Strong communication and coordination skills across Engineering, Manufacturing, Quality, and EHS Proficiency in written and spoken English Physical & Work Environment Ability to lift up to 50 lbs and work in both office and manufacturing environments Frequent presence in manufacturing, utility, and facility areas Ability to access electrical rooms, mezzanines, and confined spaces Required use of PPE and adherence to gowning protocols in controlled environments May work in cold, wet, or cleanroom environments Must be able to support shift work, weekends, and holidays Additional Requirements Ability to respond to site emergencies outside normal business hours Participation in weekend/holiday on‑call coverage as required Limited travel for training or business needs Experience leading supervisors and technical teams in a 24/7 or off‑shift environment Experience in FDA‑regulated, cGMP manufacturing environments Background in biopharmaceutical or biotechnology manufacturing preferred Demonstrated troubleshooting, incident response, or operational leadership experience EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

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