10x Genomics Single-Cell Lab Technician

Job Description

Key Responsibilities

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• Perform end-to-end single-cell sequencing workflows, including sample processing, single-cell dissociation, single-nucleus preparation, cell sorting, quality assessment, and library preparation.
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• Execute and optimize single-cell experiments using platforms such as 10x Genomics, PARSE, or other single-cell technologies.
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• Conduct molecular biology experiments including PCR, qPCR, nucleic acid extraction/purification, and NGS-related workflows.
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• Handle human and mouse tissue samples and optimize protocols for challenging samples to improve experimental performance and data quality.
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• Operate laboratory instruments including flow cytometers (FACS), cell counters, PCR/qPCR systems, and other molecular biology equipment.
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• Analyze experimental results, maintain accurate laboratory records, prepare reports, and communicate findings with internal teams and customers when required.
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• Troubleshoot experimental issues, improve laboratory workflows, and contribute to the development and validation of single-cell methodologies.
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• Collaborate with research teams and support the training or supervision of junior team members when needed.
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Requirements

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• A Master's degree with 1–3 years of relevant hands-on laboratory experience.
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• Hands-on experience with single-cell sequencing platforms (10x Genomics or equivalent) and related experimental workflows.
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Experience in

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• Single-cell suspension preparation and tissue dissociation (human/mouse tissues)
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• Single-nucleus extraction/preparation
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• Flow cytometry/FACS operation
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• Molecular biology techniques including PCR, qPCR, purification, and NGS workflows
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• Experience with protocol optimization, troubleshooting, and laboratory SOPs.
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• Familiarity with organoids, recombinant AAV, screening, or low-input molecular assays is a plus.
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• Basic experience with data analysis tools (e.g., Prism, Spotfire, or equivalent) and interest in bioinformatics is preferred.
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• Good communication skills and ability to work collaboratively in a research environment.
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• Willingness to travel when required.
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• Proficiency in English (written and spoken).
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